Meigs Syndrome Superimposed on Gorlin Syndrome in a 14-Year-Old Girl.
Meigs Syndrome Superimposed on Gorlin Syndrome in a 14-Year-Old Girl.
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DOI：
10.1016/j.jpag.2016.03.010
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发表时间：
2016-10-01
影响因子：
1.8
通讯作者：
Wakatsuki, Akihiko
中科院分区：
文献类型：
--
作者：
Iwasaki, Keita;Matsushita, Hiroshi;Wakatsuki, Akihiko
背景：梅格斯综合征是一种罕见的卵巢纤维瘤并发症。虽然卵巢纤维瘤在儿童中很少见，但在青春期后的Gorlin综合征妇女中很常见。病例：一名14岁的Gorlin综合征女孩因基底细胞癌消融而住进本院。胸部X光检查显示胸腔积液。超声检查显示双侧多结节卵巢肿块。考虑梅格斯综合征合并卵巢纤维瘤。剖腹手术发现双侧卵巢肿块，并将其切除。显微镜下，肿块由有丝分裂活跃的纤维瘤和类似血管外皮细胞瘤和黄素化卵泡膜瘤的区域组成。手术后胸腔积液很快消失。总结与结论：内科医生应考虑胸腔积液在戈林综合征患者诊断卵巢纤维瘤之前的可能性。
BACKGROUND: Meigs syndrome is a rare complication associated with ovarian fibromas. Although ovarian fibromas are rare in children, they are common in women with Gorlin syndrome after puberty.CASE: A 14-year-old girl with Gorlin syndrome was admitted to our hospital for ablation of basal cell carcinoma. A chest x-ray revealed pleural effusion. Ultrasonography revealed bilateral multinodular ovarian masses. Meigs syndrome associated with ovarian fibromas was considered. A laparotomy revealed bilateral ovarian masses, which were resected. Microscopically, the masses were composed of mitotically active fibroma and areas resembling hemangiopericytoma and luteinized thecoma. The pleural effusion disappeared soon after the surgery.SUMMARY AND CONCLUSION: Physicians should consider the possibility that pleural effusion might precede the diagnosis of ovarian fibroma in patients with Gorlin syndrome.