Phylogeny of γ-proteobacteria:: resolution of one branch of the universal tree
Phylogeny of γ-proteobacteria:: resolution of one branch of the universal tree
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DOI：
10.1002/bies.20030
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发表时间：
2004-05-01
期刊：
影响因子：
4
通讯作者：
Volker, C
中科院分区：
文献类型：
--
作者：
Brown, JR;Volker, C
细菌进化关系的重建已被证明是一项艰巨的任务，因为物种之间的变异突变率和水平基因转移（HGT）可能导致基于单个基因的系统发育树之间的严重不一致。最近，利用205个保守同源蛋白的组合序列，构建了13种γ -变形菌的高鲁棒性系统发育树。(1))只有两个蛋白的树拓扑结构不一致，这归因于假单胞菌与霍乱弧菌或肠杆菌之间的HGT。虽然这些物种之间的进化关系似乎已经解决，但进一步的分析表明，与其他细菌伴侣的HGT事件可能发生；这就改变了对γ -变形菌单系性的隐含假设。因此，任何对细菌进化的彻底重建，不仅要选择一组合适的分子标记，而且要努力减少物种选择中的潜在偏见。(C) 2004 Wiley期刊有限公司
The reconstruction of bacterial evolutionary relationships has proven to be a daunting task because variable mutation rates and horizontal gene transfer (HGT) among species can cause grave incongruities between phylogenetic trees based on single genes. Recently, a highly robust phylogenetic tree was constructed for 13 gamma-proteobacteria using the combined alignments of 205 conserved orthologous proteins.((1)) Only two proteins had incongruent tree topologies, which were attributed to HGT between Pseudomonas species and Vibrio cholerae or enterics. While the evolutionary relationships among these species appears to be resolved, further analysis suggests that HGT events with other bacterial partners likely occurred; this alters the implicit assumption of gamma-proteobacteria monophyly. Thus, any thorough reconstruction of bacterial evolution must not only choose a suitable set of molecular markers but also strive to reduce potential bias in the selection of species. (C) 2004 Wiley Periodicals, Inc.