Proof of Concept of a Novel Neck-Situated Wearable PPG System for Continuous Physiological Monitoring
Proof of Concept of a Novel Neck-Situated Wearable PPG System for Continuous Physiological Monitoring
复制标题
用于连续生理监测的新型颈部可穿戴 PPG 系统概念验证
DOI：
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发表时间：
2021
影响因子：
5.6
通讯作者：
E. Rodríguez
中科院分区：
文献类型：
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作者：
Sukhpreet Singh;Michał Kozłowski;Irene García;Zhou Jiang;E. Rodríguez
连续的夜间生命体征监测对于癫痫患者是理想的，因为在睡眠期间可能发生危及生命的低氧血症。然而，现有的生理监测系统在可用性因素和/或被采集的信号的有限信息方面受到限制。监测系统的主体位置是一个关键的考虑因素，很少被更广泛的社区所解决。本文提出了一种概念验证，颈部佩戴的光电体积描记系统，该系统的开发和测试，以评估颈部作为睡眠期间心脏和呼吸反应的纵向感测监测部位的可行性。在氧去饱和周期期间，将新系统与金标准商业多通道心肺多导睡眠图（PSG）系统进行比较，以评估其测量15名参与者的心率、呼吸率（RR）和外周血氧饱和度（SpO 2）的能力。心率的结果显示边缘平均误差为0.47次/min，95%置信度下的一致性限（LOA）在−3.17和4 bpm之间。RR比较的总体平均误差为0.43次呼吸/min，LOA在95%置信度下介于−2.73和3.3 bpm之间。最后，系统使用自定义校准方法准确输出SpO 2，在90%和100% SpO 2之间的总均方根误差为1.44%。此外，观察到颈部使得系统能够在PSG系统之前平均12.6秒检测到去饱和事件，PSG系统使用基于外周手指的PPG系统。最终，这项概念验证研究说明了基于颈部的传感在睡眠期间对心脏和呼吸器官进行微创监测的可行性。
Continuous overnight vital signs monitoring would be ideal for patients suffering from epilepsy, where life-threatening hypoxemias can occur during sleep. However, the existing physiological monitoring systems suffer from limitations in terms of usability factors and/or limited information of the signals being acquired. The body location of the monitoring system is a crucial consideration, seldom addressed by the wider community. This article presents a proof-of-concept, neck-worn photoplethysmography system, which was developed and tested to assess the feasibility of the neck as a monitoring site for longitudinal sensing of cardiac and respiratory responses during sleep. The novel system was compared against a gold-standard commercial multichannel cardiorespiratory polysomnography (PSG) system during oxygen desaturation cycles, to assess its ability to measure heart rate, respiratory rate (RR), and peripheral blood oxygen saturation (SpO2) on 15 participants. The findings for heart rate showed a marginal mean error of 0.47 beats/min with limits of agreement (LOA) at 95% confidence between −3.17 and 4 bpm. RR comparisons had an overall mean error of 0.43 breaths/min, with LOA at 95% confidence between −2.73 and 3.3 bpm. Lastly, the system accurately outputs SpO2 with an overall root-mean-square error of 1.44% between 90 and 100% SpO2 using a custom calibration method. Moreover, it was observed that the neck made it possible for the system to detect desaturation events on an average 12.6 s prior to the PSG system, which used a peripheral finger-based PPG system. Ultimately, this proof-of-concept study illustrates the viability of neck-based sensing for minimally invasive monitoring of cardiac and respiratory vitals during sleep.