Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range

Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range
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DOI:
10.1364/ol.33.001696
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发表时间:
2008-08-01
期刊:
影响因子:
3.6
通讯作者:
Rolland, Lannick P.
Rolland, Lannick P.
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Lee, Kye-Sung;Rolland, Lannick P.

文献摘要

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管状结构(诸如气管支气管树)中的内窥镜成像可以受益于具有扩展焦深(DOF)的成像光学器件,以适应跨患者和沿着同一患者内的树的管状结构的不同尺寸。然而,扩展的DOF需要在不牺牲分辨率的情况下实现,同时保持足够的灵敏度和成像速度。在这封信中,我们报告的测量分辨率和灵敏度与定制的微光学轴棱锥透镜实现,设计理论上实现一个8 rum DOE A测量不变的分辨率类似于8 μ m的证明跨4 mm测量自由度使用微光学轴棱锥,同时实现一个不变的灵敏度类似于80 dB,25 mW的输入功率。具有轴棱锥微光学透镜的双通贝塞尔光束谱域光学相干断层扫描(即,直径< 1 mm)首次在生物样品中得到证实,证明了在4 mm测量的DOF上具有不变的分辨率和信噪比,这与高斯光束成像相比。(c)2008年美国光学学会。
Endoscopic imaging in tubular structures, such as the tracheobronchial tree, could benefit from imaging optics with an extended depth of focus (DOF) to accommodate the varying sizes of tubular structures across patients and along the tree within the same patient. Yet the extended DOF needs to be accomplished without sacrificing resolution while maintaining sufficient sensitivity and speed of imaging. In this Letter, we report on the measured resolution and sensitivity achieved with a custom-made micro-optic axicon lens designed to theoretically achieve an 8 rum DOE A measured invariant resolution of similar to 8 mu m is demonstrated across a 4 mm measured DOF using the micro-optic axicon while achieving an invariant sensitivity of similar to 80 dB with a 25 mW input power. Double-pass Bessel beam spectral-domain optical coherence tomography with an axicon micro-optic lens (i.e., < 1 mm in diameter) is, for the first time to our knowledge, demonstrated in a biological sample demonstrating invariant resolution and signal-to-noise ratio across a 4 mm measured DOF, which is compared to Gaussian beam imaging. (c) 2008 Optical Society of America.