Variation of endothelial function during the menstrual cycle evaluated by flow-mediated dilatation of brachial artery
Variation of endothelial function during the menstrual cycle evaluated by flow-mediated dilatation of brachial artery
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DOI：
10.5935/1518-0557.20140022
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发表时间：
2014-10-01
影响因子：
1.5
通讯作者：
Geber, Selmo
中科院分区：
文献类型：
--
作者：
Brandao, Augusto H. F.;Serra, Paula J.;Geber, Selmo
目的：卵巢甾体激素作为血管活性物质在心血管系统中发挥作用。本研究的目的是评估内皮功能在月经周期中使用流量介导的舒张肱动脉。方法：共21名健康的绝经前妇女，定期月经周期，包括在这个观察，纵向和前瞻性研究。应用超声技术检测卵泡早期（EFP）、卵泡晚期（LFP）、黄体早期（ELP）和黄体晚期（LLP）4个月经周期时相的血管舒张功能。结果：在月经周期各时相，血管舒张反应有显著性差异（P
Objective: It is well defined that ovarian steroids play a role in the cardiovascular system, acting as vasoactive compounds. The aim of this study is to assess the endothelial function during the menstrual cycle using flow-mediated dilation of the brachial artery.Methods: A total of 21 healthy premenopausal women, with regular menstrual cycles, were included in this observational, longitudinal, and prospective study. The endothelium function was assessed by ultrasound during four phases of the menstrual cycle: early follicular phase (EFP), late follicular phase (LFP), early luteal phase (ELP) and late luteal phase (LLP).Results: We observed a significant variation among the vasodilatation response during the menstrual cycle phases (P