LINEAR-COMBINATIONS OF PRIMITIVES IN VERTEBRATE MOTOR CONTROL
LINEAR-COMBINATIONS OF PRIMITIVES IN VERTEBRATE MOTOR CONTROL
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DOI：
10.1073/pnas.91.16.7534
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发表时间：
1994-08-02
影响因子：
11.1
通讯作者：
BIZZI, E
中科院分区：
文献类型：
--
作者：
MUSSAIVALDI, FA;GISZTER, SF;BIZZI, E
对脊柱青蛙的最新研究提供了证据，表明脊髓中的神经回路被组织成许多不同的功能模块。我们已经调查了控制两个此类模块共激活的规则。为此，我们开发了一个实验范式，涉及青蛙脊髓中两个位点的同时刺激，以及对所得的机械响应的定量比较与从每个位点刺激获得的响应的总和。我们发现，两个位点的同时刺激导致每个位点分别产生的端点力的矢量总和。这种线性行为非常引人注目，并为中枢神经系统可能通过在脊髓中神经回路中存储的一些电动机的矢量叠加产生广泛的运动行为曲目。
Recent investigations on the spinalized frog have provided evidence suggesting that the neural circuits in the spinal cord are organized into a number of distinct functional modules. We have investigated the rule that governs the coactivation of two such modules. To this end, we have developed an experimental paradigm that involves the simultaneous stimulation of two sites in the frog's spinal cord and the quantitative comparison of the resulting mechanical response with the summation of the responses obtained from the stimulation of each site. We found that the simultaneous stimulation of two sites leads to the vector summation of the endpoint forces generated by each site separately. This linear behavior is quite remarkable and provides strong support to the view that the central nervous system may generate a wide repertoire of motor behaviors through the vectorial superposition of a few motor primitives stored within the neural circuits in the spinal cord.