Transcription regulates HIF-1α expression in CD4+ T cells
Transcription regulates HIF-1α expression in CD4+ T cells
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DOI：
10.1038/icb.2015.64
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发表时间：
2016-01-01
影响因子：
4
通讯作者：
Rupp, Jan
中科院分区：
文献类型：
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作者：
Bollinger, Thomas;Bollinger, Annalena;Rupp, Jan
The transcription factor hypoxia inducible factor-1 alpha (HIF-1 alpha) mediates the metabolic adaptation of cells to hypoxia and T-helper cell fate. However, HIF-1 alpha regulation in CD4(+) T cells (T cells) remains elusive. Here we observed that depletion of oxygen (O2
