Interstitial cystitis is bladder pain syndrome with Hunner's lesion
Interstitial cystitis is bladder pain syndrome with Hunner's lesion
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DOI：
10.1111/iju.12325
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发表时间：
2014-04-01
影响因子：
2.6
通讯作者：
Peeker, Ralph
中科院分区：
文献类型：
--
作者：
Fall, Magnus;Logadottir, Yr;Peeker, Ralph
间质性膀胱炎这一术语的内容和理解在过去的100年中发生了重大变化，从一种慢性、真正的炎症性膀胱疾病转变为伴随下尿路疼痛的广泛综合征。对这一发展提出了评论。从文献中的例子中，概述了经典间质性膀胱炎的一些重要特征。在后来的几十年里，更加包容的态度引起了人们对导致膀胱疼痛的各种疾病的关注。然而，不幸的是，将所有这些纳入一个方便的实体的愿望导致了许多科学和临床混乱。值得注意的是，最初间质性膀胱炎代表了Hunner型疾病。今天，人们一致认为，典型的间质性膀胱炎伴Hunner病变，即膀胱疼痛综合征3C型，根据目前的术语，是一种明确的表型；它必须在临床研究和实践中单独评估，因为治疗要求在该表现型和其他表现型之间存在重要差异。
The contents and understanding of the term, interstitial cystitis, have undergone major changes during the past 100 years, moving from a chronic, true inflammatory bladder disorder to an extensive syndrome with lower urinary tract pain. Comments on this development are presented. From examples in the literature, some important features of classic interstitial cystitis are outlined. The more inclusive attitude of later decades has drawn desirable attention to the entire spectrum of disorders resulting in bladder pain. The wish to include all of them into one handy entity has unfortunately resulted in much scientific and clinical confusion, though. It is noted that originally interstitial cystitis represented the Hunner type of disease. Today, there is agreement that the classic type of interstitial cystitis with Hunner's lesions, bladder pain syndrome type 3C according to current terminology, stands out as a well-defined phenotype; it has to evaluated separately in clinical studies and practice, as treatment requirements differ importantly between this and other phenotypes.