Comparison of skin perfusion response with alternating and constant pressures in people with spinal cord injury

Comparison of skin perfusion response with alternating and constant pressures in people with spinal cord injury
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DOI:
10.1038/sc.2010.58
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发表时间:
2011-01-01
期刊:
影响因子:
2.2
通讯作者:
Brenes, G.
Brenes, G.
中科院分区:
医学3区
文献类型:
--
作者:
Jan, Y-K;Brienza, D. M.;Brenes, G.

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研究设计:双向析因混合设计,受试者间因素为脊髓损伤(SCI)状态(SCI和非SCI),受试者内因素为压力模式(交变压力和恒定压力)。目的:比较交变压力和恒定压力对脊髓损伤患者负重组织血流灌注的影响,并应用于改善交变压力支撑面的使用。地点:大学研究实验室。对象:28名参与者,7名颈椎损伤患者,7名T6以下损伤患者和14名健康对照。方法:采用激光多普勒血流仪连续测定10分钟预负荷下,20分钟加载(交变或恒压)和10分钟后加载。施加交变压力,低界面压力为0 mm Hg,高界面压力为60 mm Hg,循环时间为5min;恒定压力,界面压力为30 mm Hg。结果:压力模式影响负重组织的皮肤血流灌注反应(P
Study design: Two-way factorial mixed design, the between-subjects factor as the spinal cord injury (SCI) status (SCI and non-SCI) and the within-subjects factor as the pressure pattern (alternating and constant pressures).Objectives: To compare the effects of alternating and constant pressures on weight-bearing tissue perfusion in people with SCI, with application for improving alternating pressure support surface usage.Setting: University research laboratory.Subjects: A total of 28 participants were studied, 7 participants with cervical injury, 7 participants with injury below T6 and 14 healthy controls.Methods: Sacral skin perfusion was continuously measured using laser Doppler flowmetry under 10 min preloading, 20 min loading (alternating or constant pressures) and 10 min postloading. Alternating pressure was applied with low-interface pressure at 0 mm Hg and high-interface pressure at 60 mm Hg with a cycle time of 5 min; constant pressure was applied with interface pressure at 30 mm Hg.Results: The results showed that pressure pattern affects skin perfusion responses in weight-bearing tissues (P