Visualization of neuronal activity in monkey striate cortex.

Visualization of neuronal activity in monkey striate cortex.
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猴子纹状皮层神经元活动的可视化。

DOI:
10.1146/annurev.ph.51.030189.003021
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发表时间:
1989
影响因子:
18.2
通讯作者:
Blasdel,GG
Blasdel,GG
中科院分区:
医学1区
文献类型:
--
作者:
Blasdel,GG

文献摘要

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开发了视频成像策略,以绘制特定视觉刺激在猴子纹状皮质中产生的活动模式。所有的实验都是从传统的电生理记录开始的,以确保皮质细胞是健康的,并记录正常反应特性的实例(例如,定向选择性、眼睛优势),以便与后来获得的神经元活动的光学图像进行比较。视频成像的结果显示了取向偏好如何在大脑皮层表面分布,并表明这种分布具有二维斑块和一维边界的特征。重复观察同一块组织的能力,在某些情况下需要几周的时间,这使得视频成像方法成为研究皮质发育的理想方法。
Developed video imaging strategies to map activity patterns generated by specific visual stimuli in monkey striate cortex. All experiments began with conventional electrophysiological recordings to ensure that cortical cells were healthy and to document instances of normal response properties (eg, orientation selectivity, ocular dominance) for comparison with the optical images of neuronal activity obtained later. Results of the video imaging show how orientation preferences are distributed across the cortical surface and indicate that this distribution is characterized by 2-dimensional patches and 1-dimensional borders. The ability to look repeatedly at the same piece of tissue, in some cases over a period of weeks, makes the video imaging approach ideal for studies of cortical development.(PsycINFO Database Record (c) 2016 APA, all rights reserved)