Localization of thrombomodulin in a rabbit eye.
Localization of thrombomodulin in a rabbit eye.
复制标题
兔眼中血栓调节蛋白的定位。
作者：
H. Kawamura;Y. Hiramatsu;I. Watanabe
PURPOSE
To show the distribution of an anticoagulant factor, thrombomodulin, in a rabbit eye.
METHODS
Immunohistochemical staining using polyclonal anti-rabbit thrombomodulin antibody was performed with the excised eyes of pigmented adult rabbits. Streptavidin-biotin method was used to obtain intense staining.
RESULTS
The endothelium of the chorioretinal vessels showed positive linear staining. The ciliary non-pigmented epithelium showed granular staining, while the pigmented epithelium stained negatively. The positive staining was also detected in the trabecular plexus endothelium. The vascular endothelium of the ciliary body stained weakly.
CONCLUSIONS
It is suggested that thrombomodulin in the vessel walls and the aqueous drainage apparatus works to maintain normal blood fluidity and aqueous outflow. The role of nonvascular thrombomodulin in the ciliary non-pigmented epithelium is unclear.
DOI：
10.1073/pnas.78.4.2249
发表时间：
1981-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
ESMON, CT;OWEN, WG
通讯作者：
OWEN, WG