Risk factors for urinary incontinence among middle-aged women

Risk factors for urinary incontinence among middle-aged women
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DOI:
10.1016/j.ajog.2005.07.051
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发表时间:
2006-02-01
影响因子:
9.8
通讯作者:
Grodstein, F
Grodstein, F
中科院分区:
医学1区
文献类型:
--
作者:
Danforth, KN;Townsend, MK;Grodstein, F

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目的:本研究的目的是确定中年女性尿失禁的危险因素。研究设计:我们对 83,355 名护士健康研究 II 参与者进行了横断面分析。自 1989 年以来,妇女通过邮寄问卷提供健康信息; 2001年,年龄在37岁至54岁之间的人被要求提供有关尿失禁的信息。我们使用逻辑回归检查了调整后的失禁比值比。结果:43% 的女性报告有失禁。调整后,与白人女性相比,黑人(比值比,0.49;95% CI,0.40-0.60)和亚裔美国女性(比值比,0.57;95% CI,0.46-0.72)严重失禁的几率降低。年龄增加、体重指数、产次、当前吸烟、2型糖尿病和子宫切除术均与失禁呈正相关。 50至54岁女性发生严重尿失禁的几率是<40岁女性的1.81倍(95% CI,1.66-1.97);体重指数 >= 30 kg/m(2) 的女性发生严重尿失禁的几率是体重指数 22 至 24 kg/m(2) 的女性的 3.10 倍(95% CI,2.91-3.30)。结论:尿失禁在这些中年女性中非常普遍。潜在的危险因素包括年龄、种族/民族、体重指数、产次、吸烟、糖尿病和子宫切除术。 (c) 2006 Mosby, Inc. 保留所有权利。
Objective: The purpose of this study was to identify risk factors for urinary incontinence in middle-aged women.Study design: We conducted a cross-sectional analysis of 83,355 Nurses' Health Study II participants. Since 1989, women have provided health information on mailed questionnaires; in 2001, at the ages 37 to 54 years, information on urinary incontinence was requested. We examined adjusted odds ratios of incontinence using logistic regression.Results: Forty-three percent of the women reported incontinence. After adjustment, black (odds ratio, 0.49; 95% CI, 0.40-0.60) and Asian-American women (odds ratio, 0.57; 95% CI, 0.46-0.72) were at reduced odds of severe incontinence compared with white women. Increased age, body mass index, parity, current smoking, type 2 diabetes mellitus, and hysterectomy all were associated positively with incontinence. Women who were aged 50 to 54 years had 1.81 times the odds of severe incontinence compared with women who were < 40 years old (95% CI, 1.66-1.97); women with a body mass index of >= 30 kg/m(2) had 3.10 times the odds of severe incontinence compared with a body mass index of 22 to 24 kg/m(2) (95% CI, 2.91-3.30).Conclusion: Urinary incontinence is highly prevalent among these middle-aged women. Potential risk factors include age, race/ethnicity, body mass index, parity, smoking, diabetes mellitus, and hysterectomy. (c) 2006 Mosby, Inc. All rights reserved.