An easily reproducible, hand-held, single-sided, MRI sensor

An easily reproducible, hand-held, single-sided, MRI sensor
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DOI:
10.1016/j.jmr.2019.106591
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发表时间:
2019-11-01
影响因子:
2.2
通讯作者:
Mandal, Soumyajit
Mandal, Soumyajit
中科院分区:
化学3区
文献类型:
--
作者:
Greer, Mason;Chen, Cheng;Mandal, Soumyajit

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单面核磁共振传感器允许对比磁铁更大的样本进行成像。因此,它们使真正的便携式成像仪在医学、质量保证(QA)、农业、材料科学和其他领域具有潜在的应用。然而,尽管最近取得了一些进展,但单侧MRI系统相对较少。这部分是由于商业产品数量有限。此外,当前的实施方案通常需要大型和/或复杂的磁体阵列,这需要诸如铣削或钻孔之类的加工技术。这些技术必须严格按照公差执行,以确保B0场的精度。此外,这些系统通常具有手工缠绕的射频或梯度线圈,这些线圈的构建并不容易。这项工作的主要目标是减小单面核磁共振传感器的尺寸,同时使其他人更容易建造它们。为此,我们提出了一种手持式单面磁共振传感器,它使用易于组装的磁体阵列、3D打印外壳和包含射频线圈、梯度线圈和匹配网络的印刷电路板(PCB)构建。通过直接在电路板上实现所有线圈,可以很容易地优化几何结构,然后以低成本制造。给出了不同样品的自旋密度加权图像和T-1加权图像,以验证所提出的传感器的能力。(C)2019 Elsevier Inc.保留所有权利。
Single-sided MRI sensors allow the imaging of samples that are larger than the magnet. Thus, they enable truly portable imagers with potential applications in medicine, quality assurance (QA), agriculture, material science, and other fields. However, despite recent advancements, single-sided MRI systems are relatively uncommon. This is partially due to the limited number of commercial products. Also, current implementations often require large and/or complex magnet arrays which require machining techniques such as milling or drilling. These techniques must be performed to tight tolerances to ensure accuracy of the B0 field. Furthermore, these systems generally have hand-wound RF or gradient coils that are not trivial to construct. The main goals of this work are to reduce the size of single-sided MRI sensors while simultaneously making them more accessible for others to build. To this end, we present a hand-held, single-sided, MRI sensor that is constructed using an easy-to-assemble magnet array, a 3D-printed housing, and printed circuit boards (PCBs) that contain the RF coil, gradient coils, and matching network. By implementing all coils directly on PCBs, the geometry can be easily optimized and then manufactured at low cost. Both spin density-weighted and T-1-weighted images of various samples are presented to demonstrate the capabilities of the proposed sensor. (C) 2019 Elsevier Inc. All rights reserved.