Evaluation of the adjunctive effect of platelet-rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six-month results of a randomized, split-mouth, controlled clinical study.
Evaluation of the adjunctive effect of platelet-rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six-month results of a randomized, split-mouth, controlled clinical study.
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DOI：
10.1111/jcpe.12598
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发表时间：
2016-11
影响因子：
6.7
通讯作者：
Humerya Aydemir Turkal;S. Demirer;A. Dolgun;H. G. Keceli
中科院分区：
文献类型：
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作者：
Humerya Aydemir Turkal;S. Demirer;A. Dolgun;H. G. Keceli
目的比较釉基质衍生物（elaminmatrixderivatives，EMD）和EMD +富血小板纤维蛋白（platelet-rich fibrin，PRF）治疗慢性牙周炎患者骨内缺损（intrabolic defects，IBD）的效果。材料与方法：采用裂口设计，28对IBD患者随机接受EMD或EMD + PRF治疗。分别于治疗前（BL）和治疗后6个月测量临床附着水平（CAL）、探诊深度（PD）、牙龈退缩（GR）、缺损深度（DD）、缺损宽度（DW）和缺损角度（DA）。结果EMD组和EMD + PRF组的BL临床和影像学测量结果相似。虽然术后测量显示两组的PD和CAL均显著降低，但未检测到组间差异。当比较EMD和EMD + PRF组时，缺损填充也没有统计学差异。结论：两种疗法均显著改善了IBD治疗的临床效果。添加PRF并未改善临床和影像学结局。
AIM This study aimed to compare the results obtained with enamel matrix derivative (EMD) and EMD + platelet-rich fibrin (PRF) in the treatment of intrabony defects (IBDs) in chronic periodontitis patients. MATERIALS AND METHODS Using a split-mouth design, 28 paired IBDs were randomly treated either with EMD or with EMD + PRF. Clinical and radiographic measurements including clinical attachment level (CAL), probing depth (PD), gingival recession (GR), defect depth (DD), defect width (DW) and defect angle (DA) were recorded at baseline (BL) and at six months following therapy. RESULTS BL clinical and radiographic measurements were similar for EMD and EMD + PRF groups. Although postsurgical measurements revealed significant reduction for PD and CAL in both groups, no intergroup difference was detected. When EMD and EMD + PRF groups were compared, defect fill was not also statistically different. CONCLUSIONS Both therapies resulted in significant clinical improvement in IBD treatment. Addition of PRF did not improve the clinical and radiographic outcomes.