ANTIOXIDATIVE CAFFEOYLQUINIC ACID-DERIVATIVES IN THE ROOTS OF BURDOCK (ARCTIUM-LAPPA L)
ANTIOXIDATIVE CAFFEOYLQUINIC ACID-DERIVATIVES IN THE ROOTS OF BURDOCK (ARCTIUM-LAPPA L)
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DOI：
10.1021/jf00058a007
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发表时间：
1995-10-01
影响因子：
6.1
通讯作者：
NIKI, R
中科院分区：
文献类型：
--
作者：
MARUTA, Y;KAWABATA, J;NIKI, R
从牛蒡根中分离得到5个具有抗氧化活性的咖啡酰奎尼酸衍生物，日本的一种可食用植物。它们的结构分别为1-O-，5-O-二咖啡酰基奎宁酸（1），1-O-，5-O-二咖啡酰基-3-O-琥珀酰基奎宁酸（2），1-O-，5-O-二咖啡酰基-4-O-琥珀酰基奎宁酸（3），1-O-，5-O-二咖啡酰基-3-O-，4-O-二琥珀酰基奎宁酸（4）和1-O-，3-O-，5-O-三咖啡酰基-4-O-琥珀酰基奎尼酸（5）的化学和光谱（NMR，MS）的基础上的证据。在自由基引发剂存在下，在亚油酸甲酯的己烷/2-丙醇溶液中测量抗氧化活性。抗氧化效率的顺序为α-生育酚<绿原酸<咖啡酸<（1）=（2）=（3）=（4）<（5）。
Five antioxidative caffeoylquinic acid derivatives were isolated from the roots of burdock (Arctium lappa L.), an edible plant in Japan. Their structures were established as 1-O-,5-O-dicaffeoylquinic acid (1), 1-O-,5-O-dicaffeoyl-3-O-succinylquinic acid (2), 1-O-,5-O-dicaffeoyl-4-O-succinylquinic acid (3), 1-O-,5-O-dicaffeoyl-3-O-,4-O-disuccinylquinic acid (4), and 1-O-,3-O-,5-O-tricaffeoyl-4-O-succinylquinic acid (5) on the basis of chemical and spectral (NMR, MS) evidence. The antioxidant activities were measured in a hexane/2-propanol solution of methyl linoleate in the presence of a radical initiator. The antioxidant efficiency increased in the order of alpha-tocopherol < chlorogenic acid < caffeic acid < (1) = (2) = (3) = (4) < (5).