Invited review: Novel methods and perspectives for modulating the rumen microbiome through selective breeding as a means to improve complex traits: Implications for methane emissions in cattle
Invited review: Novel methods and perspectives for modulating the rumen microbiome through selective breeding as a means to improve complex traits: Implications for methane emissions in cattle
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特邀评论：通过选择性育种调节瘤胃微生物组作为改善复杂性状的一种手段的新方法和观点：对牛甲烷排放的影响
DOI：
10.1016/j.livsci.2023.105171
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发表时间：
2023
影响因子：
1.8
通讯作者：
González-Recio O
中科院分区：
文献类型：
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作者：
González-Recio O
瘤胃微生物组是反刍动物甲烷排放的主要原因。在过去的十年里，瘤胃微生物的研究引起了人们极大的兴趣。高通量测序技术是通过宏基因组研究扩大对瘤胃微生物的了解的关键。大量证据表明，瘤胃微生物群的组成受宿主基因型的影响。因此，微生物群的调节为大型和小型反刍动物的低排放育种提供了重要工具。宏基因组研究的主要挑战，并提出了一些解决方案时，可用的，包括宏基因组信息纳入统计模型中经常使用的动物育种。为了将微生物组信息纳入育种计划，必须考虑瘤胃微生物组的特殊性，从采样到纳入选择指数。本文综述了这一领域的最新进展。
The rumen microbiome is responsible for methane emission in ruminants. The study of microbes in the rumen has attracted great interest in the last decade. High-throughput sequencing technologies have been key in expanding the knowledge of the microorganisms that populate the rumen through metagenomic studies. There is substantial evidence that the composition of the rumen microbiota is influenced by host genotype. Therefore, modulation of the microbiota poses an important tool for breeding for lower emissions in large and small ruminants. The main challenges of metagenomic studies are addressed and some solutions are proposed when available, including the incorporation of metagenomic information into statistical models regularly used in animal breeding. To incorporate microbiome information into breeding programs, the particularities of the rumen microbiome must be considered, from sampling to inclusion in selection indices. The latest advances in this area are discussed in this review.