The TAS-20 more likely measures negative affects rather than alexithymia itself in patients with major depression, panic disorder, eating disorders and substance use disorders
The TAS-20 more likely measures negative affects rather than alexithymia itself in patients with major depression, panic disorder, eating disorders and substance use disorders
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DOI：
10.1016/j.comppsych.2013.12.008
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发表时间：
2014-05-01
影响因子：
7.3
通讯作者：
De Panfilis, Chiara
中科院分区：
文献类型：
--
作者：
Marchesi, Carlo;Ossola, Paolo;De Panfilis, Chiara
背景：本研究评估了重度抑郁症（MD）、惊恐障碍（PD）、饮食障碍（ED）和物质使用障碍（SUD）患者在焦虑和抑郁严重程度控制后，多伦多述情障碍量表20项（TAS-20）与健康对照组的差异是否持续存在。方法：MD患者38例，PD患者58例，ED患者52例，SUD患者30例，健康对照78例(C)，分别完成TAS-20、汉密尔顿焦虑量表（Ham-A）、汉密尔顿抑郁量表（Ham-D）。结果：在控制焦虑和抑郁严重程度的影响后，不论其障碍类型，患者组与对照组之间的TAS-20评分差异均消失。相比之下，在排除述情水平的影响后，患者和对照组之间焦虑和抑郁严重程度的差异仍然存在。结论：我们的数据表明，由TAS-20测量的述情水平受到症状严重程度的调节，支持述情障碍可以代表MD、PD、ED和SUD患者的一种状态现象的观点，因为TAS-20似乎对一般窘迫综合征过于敏感，它更可能测量负面影响，而不是述情障碍本身。(C) 2014爱思唯尔公司版权所有。
Background: This study evaluates whether the difference in Toronto Alexithymia Scale-20 item (TAS-20) between patients with major depression (MD), panic disorder (PD), eating disorders (ED), and substance use disorders (SUD) and healthy controls persisted after controlling for the severity of anxiety and depression.Methods: Thirty-eight patients with MD, 58 with PD, 52 with ED, and 30 with SUD and 78 healthy controls (C) completed the TAS-20, the Hamilton Rating Scale for Ankiety (Ham-A), the Hamilton Rating Scale for Depression (Ham-D).Results: The differences in TAS-20 scores observed between patient groups, regardless of the type of their disorders, and controls disappeared after controlling for the effect of anxiety and depression severity. In contrast, the differences in severity of anxiety and depression between patients and controls were still present, after excluding the effect of alexithymic levels.Conclusions: Our data suggest that alexithymic levels, as measured by the TAS-20, are modulated by the severity of symptoms, supporting the view that alexithymia can represent a state phenomenon in patients with MD, PD, ED and SUD, because the TAS-20 seems overly sensitive to a general distress syndrome, and it is more likely to measure negative affects rather than alexithymia itself. (C) 2014 Elsevier Inc. All rights reserved.