Flavin Adenine Dinucleotide Photochemistry Is Magnetic Field Sensitive at Physiological pH
Flavin Adenine Dinucleotide Photochemistry Is Magnetic Field Sensitive at Physiological pH
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DOI：
10.1021/acs.jpclett.8b01088
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发表时间：
2018-05-17
影响因子：
5.7
通讯作者：
Woodward, Jonathan R.
中科院分区：
文献类型：
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作者：
Antill, Lewis M.;Woodward, Jonathan R.
我们提供了黄素腺嘌呤二核苷酸 (FAD) 在 pH 范围 2.3 至 8.0 的水溶液中蓝光激发后光化学的时间分辨光吸收和磁场效应数据。 FAD 在基态、激发单线态和自由基对态中的闭合形式构象的影响对观察到的动力学和磁场依赖性表现出显着影响，并且值得注意的是，即使在生理 pH 值下也观察到磁场效应，其中 FAD 自由基对的磁场敏感性仅比 pH 2.3 时低 75%。
We present time-resolved optical absorption and magnetic field effect data on the photochemistry following blue light excitation of flavin adenine dinucleotide (FAD) in aqueous solution in the pH range 2.3 to 8.0. Effects of closed form conformations of FAD in ground, excited singlet, and radical pair states exhibit significant influence on the observed kinetics and magnetic field dependence and remarkably, magnetic field effects are observed even at physiological pH where the FAD radical pairs are only 75% less magnetic field sensitive than at pH 2.3.