Spectroscopic spectral-domain optical coherence microscopy

Spectroscopic spectral-domain optical coherence microscopy
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DOI:
10.1364/ol.31.001079
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发表时间:
2006-04-15
期刊:
影响因子:
3.6
通讯作者:
Boppart, SA
Boppart, SA
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Xu, CY;Vinegoni, C;Boppart, SA

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The spectroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells. (c) 2006 Optical Society of America.