One double-stranded DNA probes as classifier of multi targeting strand
One double-stranded DNA probes as classifier of multi targeting strand
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DOI：
10.1109/mhs.2014.7006166
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发表时间：
2014-11
期刊：
影响因子：
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通讯作者：
A. Wibowo;K. Sekiyama
中科院分区：
文献类型：
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作者：
A. Wibowo;K. Sekiyama
在本文中，我们研究了一种替代双链探针（dsProbe）系统作为检测平台，该系统在 DNA 链置换反应中采用基于相似性的分类器。我们将基于 DNA 立足点域的标签传播制定为分类器，其中节点根据其邻近度传播到相邻节点。我们观察 DNA 链序列的错配属性来认识该模型的效果。属性是不匹配的位置、长度和位置数量。我们使用 Nupack 软件进行模拟并进行实验研究。
In this paper, we investigate an alternative double-stranded probe (dsProbe) system as detection platform that employs a similarity-based classifiers in DNA strand displacement reactions. We formulate label propagation based on DNA toehold domain as classifier, where a node propagates to neighboring nodes according to their proximity. We observe mismatch attributes of DNA strand sequences to recognize the effect of this model. The attributes are position, length and location number of mismatches. We carry out simulation using Nupack software and also experimental investigation..