[Clinical, anatomical and biophysical data on a case of encephalopathy with aluminum deposits].
[Clinical, anatomical and biophysical data on a case of encephalopathy with aluminum deposits].
复制标题
[一例铝沉积性脑病的临床、解剖和生物物理数据]。
DOI：
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发表时间：
1975
影响因子：
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通讯作者：
L. Cartier
中科院分区：
文献类型：
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作者：
J. Lapresle;S. Duckett;P. Gallé;L. Cartier
一名男子在27岁时出现神经和精神渐进式恶化的最初迹象，最终导致他在37岁时死于并发肺部感染。他是个严重的酒鬼。脑部病理检查显示斑片状脱髓鞘和晶体物质沉积，类似于所谓的钙化。生物物理检查显示，在大脑和其他器官中，所有沉积物中都存在铝和磷，有时还伴有铁、硫和钙。他过去的记录没有显示他接触过铝。推测这是一个“广泛性铝中毒”的病例，主要的临床和病理特征表现在中枢神经系统。
A man presented at 27 years of age, the first signs of a progressive neurological and mental deterioration which eventually lead to his death at 37, from an intercurrent pulmonary infection. He was a severe alcoholic. The pathological examination of the brain revealed patchy demyelination and deposits of crystalline material, resembling so called calcifications. The biophysical examination showed the presence in the brain and other organs, of aluminum and phosphorus in all deposits, sometimes associated with iron, sulfur and calcium. Nothing in his past history suggests any contact with aluminum. Presumably this is a case of "generalized aluminosis", with the main clinical and pathological features manifesting in the central nervous system.