Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway.
Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway.
复制标题
PD-1检查点途径的分子和生化方面。
DOI:
10.1056/nejmra1514296
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发表时间:
2016-11-03
期刊:
影响因子:
--
通讯作者:
Boussiotis VA
中科院分区:
文献类型:
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作者:
Boussiotis VA
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.