Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway.

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway.
复制标题

PD-1检查点途径的分子和生化方面。

DOI:
10.1056/nejmra1514296
复制
发表时间:
2016-11-03
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
Boussiotis VA
Boussiotis VA
中科院分区:
其他
文献类型:
--
作者:
Boussiotis VA

文献摘要

被引文献

相似文献

PD-1通路在维持免疫自身耐受中起着重要作用。然而,癌症可以破坏这一途径的作用,并使免疫系统对它们的存在视而不见。对该途径的分子细节进行了讨论。
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.