Alpha-Beta and Gamma Rhythms Subserve Feedback and Feedforward Influences among Human Visual Cortical Areas.
Alpha-Beta and Gamma Rhythms Subserve Feedback and Feedforward Influences among Human Visual Cortical Areas.
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DOI：
10.1016/j.neuron.2015.12.018
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发表时间：
2016-01-20
期刊：
影响因子：
16.2
通讯作者：
Fries P
中科院分区：
文献类型：
--
作者：
Michalareas G;Vezoli J;van Pelt S;Schoffelen JM;Kennedy H;Fries P
灵长类动物的视觉皮层是分层组织的。自下而上和自上而下的影响通过不同的频率通道施加，正如最近在猕猴中通过将区域间影响与层流解剖投影模式相关联所揭示的那样。由于这种解剖数据无法在人类受试者中获得，因此我们选择了7个与人类相同的猕猴视觉区域，并将猕猴的层流投影模式与脑磁图测量的人类区域间定向影响相关联。我们表明，沿前馈投影的影响在伽马波段占主导地位，而沿反馈投影的影响在α - β波段占主导地位。有节奏的区域间影响限制了人类七个同源视觉区域的功能层次结构，这与猕猴各自的解剖层次结构密切一致。节奏影响允许将层次结构扩展到26个人类视觉区域，包括独特的人类大脑区域。腹侧和背侧流视觉区域的等级水平受到α - β波段区域间影响的不同影响。
Primate visual cortex is hierarchically organized. Bottom-up and top-down influences are exerted through distinct frequency channels, as was recently revealed in macaques by correlating inter-areal influences with laminar anatomical projection patterns. Because this anatomical data cannot be obtained in human subjects, we selected seven homologous macaque and human visual areas, and correlated the macaque laminar projection patterns to human inter-areal directed influences as measured with magnetoencephalography. We show that influences along feedforward projections predominate in the gamma band, whereas influences along feedback projections predominate in the alpha-beta band. Rhythmic inter-areal influences constrain a functional hierarchy of the seven homologous human visual areas that is in close agreement with the respective macaque anatomical hierarchy. Rhythmic influences allow an extension of the hierarchy to 26 human visual areas including uniquely human brain areas. Hierarchical levels of ventral and dorsal stream visual areas are differentially affected by inter-areal influences in the alpha-beta band.