[Cause analysis and treatment strategies of "recurrence" with novel coronavirus pneumonia (COVID-19) patients after discharge from hospital].
[Cause analysis and treatment strategies of "recurrence" with novel coronavirus pneumonia (COVID-19) patients after discharge from hospital].
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DOI：
10.3760/cma.j.cn112147-20200229-00219
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发表时间：
2020-04-12
期刊：
影响因子：
--
通讯作者：
Liu, H G
中科院分区：
文献类型：
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作者：
Zhou, L;Liu, K;Liu, H G
随着大量COVID-19患者出院，部分患者在出院后出现再次发热和核酸检测阳性。这可能与2019-nCoV的生物学特性有关，也可能与患者的基础疾病、临床状态、糖皮质激素使用、样本采集、处理和检测有关，有些甚至与再次感染或继发细菌病毒感染有关。因此，我们建议针对这一现象，在指南的基础上，进一步对出院进行分层管理，尤其是对高龄、基础疾病或重症、危重症肺炎患者。对于住院后较长时间不能完全康复的患者，应采取个体化的治疗方法和不同的出院评价标准，确保患者完全治愈，防止出院后复发。
With a large number of COVID-19 patients discharging from hospital, some had showed re-fever and positive nucleic acid test after discharge from hospital. This might be due to the biological characteristics of 2019-nCoV, and might also be related to the basic disease, clinical status, glucocorticoid using, sample sampling, processing and detecting of patients, and some even related to the re-infection or secondary bacterial virus infection. Therefore, we suggest that in view of this phenomenon, further stratified management of discharge from hospital should be carried out on the basis of guidelines, especially for patients with advanced age, underlying diseases or severe or critical pneumonia. For those patients who can't completely deoxygenate for a long time after hospitalization, individualized treatment methods and different discharge evaluation criteria should be adopted to ensure the complete cure of patients and prevent recurrencing after discharge from hospital.