Quality of life after radical treatment of prostate cancer: Validation of the Italian version of the university of California-Los Angeles Prostate Cancer Index
Quality of life after radical treatment of prostate cancer: Validation of the Italian version of the university of California-Los Angeles Prostate Cancer Index
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DOI：
10.1016/j.urology.2005.02.027
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发表时间：
2005-08-01
期刊：
影响因子：
2.1
通讯作者：
Gacci, M
中科院分区：
文献类型：
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作者：
Gacci, M;Livi, L;Gacci, M
目标。验证意大利版加州大学洛杉矶分校前列腺癌指数（UCLA-PCI）。我们回顾性地选择了接受根治性耻骨后前列腺切除术（RRP）或外束放疗（EBR）治疗的前列腺癌患者。每位受试者被要求填写UCLA-PCI简短表格和36项简短健康调查问卷（SF-36）（主样本）；一个小组完成两次问卷调查（重新测试样本）。进行了语言翻译和验证。分析了心理测量特征。共有595名男性被纳入研究：394名来自泌尿科（RRP治疗），201名来自放疗科（EBR治疗）。其中，75例患者（50例来自RRP组，25例来自EBR组）被选为重测队列。SF-36和UCLA-PCI在手术和放疗人群主要样本中的内部一致性信度范围为0.82 - 0.94；主要泌尿外科组的性功能平均值优于主要放射治疗组，而主要放射治疗组的泌尿功能和泌尿系统平均值优于主要放射治疗组。据报道，仅在接受RRP治疗的患者中，尿功能与性功能和肠道功能之间，以及尿功能与所有尿量表之间存在很强的相关性。据报道，EBR组的性功能和性困扰之间存在预期的相关性，而RRP组则没有。我们的研究证明了意大利语版UCLA-PCI具有优异的心理测量特性；意大利语版UCLA-PCI问卷将允许对前列腺癌患者进行跨文化比较研究。
Objectives. To validate an Italian version of the University of California-Los Angeles Prostate Cancer Index (UCLA-PCI).Methods. Men with prostate cancer treated with radical retropubic prostatectomy (RRP) or external beam radiation (EBR) were retrospectively selected. Each subject was asked to complete the UCLA-PCI short form and the 36-item short-form health survey (SF-36) questionnaires (principal sample); a subgroup completed both questionnaires twice (retest sample). A linguistic translation and validation was performed. Psychometric properties were analyzed.Results. A total of 595 men were included in the study: 394 from the Department of Urology (treated with RRP) and 201 from the Department of Radiotherapy (treated with EBR). Of these, 75 patients (50 from the RRP group and 25 from the EBR group) were selected as the retest cohort. Internal consistency reliability of the SF-36 and UCLA-PCI for the primary sample of the surgery and radiotherapy populations ranged from 0.82 to 0.94; the mean values of sexual function were superior in the principal urology group, whereas the principal radiotherapy group demonstrated superior mean values of urinary function and urinary bother. A strong correlation between urinary function and sexual and bowel function, and between urinary function and all bother scales, was reported only for patients treated with RRP. The expected correlation between sexual function and sexual bother was reported for the EBR group but not for the RRP group.Conclusions. Our study demonstrated the excellent psychometric properties of the Italian version of the UCLA-PCI; the Italian version of the UCLA-PCI questionnaire will allow cross-cultural comparative studies in men with prostate cancer.