Ultrasonography is a sensitive tool for monitoring localized scleroderma
Ultrasonography is a sensitive tool for monitoring localized scleroderma
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DOI：
10.1093/rheumatology/kem120
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发表时间：
2007-08-01
期刊：
影响因子：
5.5
通讯作者：
Haines, K. A.
中科院分区：
文献类型：
--
作者：
Li, S. C.;Liebling, M. S.;Haines, K. A.
Objective.探讨超声检查（USG）监测儿童局限性硬皮病（LS）的有效性。对6例LS有USG的儿科患者进行回顾性病历审查。USG在活动性病变中检测到几种异常，包括血流量增加、回声增强和皮下脂肪丢失。USG结果与临床评估一致，并记录了治疗期间皮下脂肪的再生和病变尺寸的缩小。在1例患者中，USG比磁共振评估更敏感。发现USG是评估儿科患者LS病变活动性和程度的敏感工具。需要进一步的研究来评估其监测这些患者的普遍适用性。
Objective. To examine the usefulness of ultrasonography (USG) for monitoring paediatric localized scleroderma (LS).Methods. A retrospective chart review of six paediatric patients who had USG of their LS.Results. USG detected several abnormalities in active lesions including increased blood flow, increased echogenicity and loss of subcutaneous fat. USG findings corresponded with clinical assessment, and documented regeneration of subcutaneous fat and reduction in lesion size during treatment. In one patient, USG was more sensitive than magnetic resonance evaluation.Conclusion. USG was found to be a sensitive tool for assessing the activity and extent of LS lesions in paediatric patients. Further studies are needed to assess its general applicability for monitoring these patients.