Chromogranin A is present in and released by fish endocrine tissue.
Chromogranin A is present in and released by fish endocrine tissue.
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嗜铬粒蛋白 A 存在于鱼类内分泌组织中并由其释放。
DOI：
10.1016/0024-3205(87)90002-6
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发表时间：
1987
期刊：
影响因子：
6.1
通讯作者：
D. Copp
中科院分区：
文献类型：
--
作者：
L. Deftos;B. Björnsson;D. Burton;D. O'Connor;D. Copp
嗜铬粒蛋白A （Chromogranin A, CgA）是一种存在于许多哺乳动物内分泌细胞中的蛋白质，并与其常驻激素共同分泌。我们通过免疫组织学证实了CgA存在于虹鳟鱼的鳃末梢腺和小体中。用放射线免疫法测定了coho salmon鱼鳃腺培养培养基中CgA的含量。我们的观察结果表明，CgA存在于进化不同物种的内分泌腺中。这些观察结果与CgA参与多种激素分泌过程的假设是一致的。
Chromogranin A (CgA) is a protein that is present in many mammalian endocrine cells and co-secreted with their resident hormones. We have demonstrated the presence of CgA by immunohistology in the ultimobranchial glands and corpuscles of Stannius of rainbow trout. CgA was also detected by radioimmunoassay in the medium of incubated coho salmon ultimobranchial glands. Our observations demonstrate the presence of CgA in endocrine glands of evolutionarily divergent species. These observations are consistent with the hypothesis that CgA participates in the secretory process of a wide variety of hormones.
克隆的嗜铬粒蛋白 A (CgA) cDNA 可检测多种神经内分泌组织中的 2.3Kb mRNA。
DOI：
10.1016/0006-291x(86)91226-x
发表时间：
1986
影响因子：
3.1
作者：
Deftos,LJ;Murray,SS;Burton,DW;Parmer,RJ;O'Connor,DT;Delegeane,AM;Mellon,PL
通讯作者：
Mellon,PL
影响因子：
158.5
作者：
OCONNOR, DT;DEFTOS, LJ
通讯作者：
DEFTOS, LJ
影响因子：
39.2
作者：
SOBOL, RE;OCONNOR, DT;DEFTOS, LJ
通讯作者：
DEFTOS, LJ