A review of the spectrum of clinical ocular fundus findings in P-falciparum malaria in African children with a proposed classification and grading system

A review of the spectrum of clinical ocular fundus findings in P-falciparum malaria in African children with a proposed classification and grading system
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DOI:
10.1016/s0035-9203(99)90071-8
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发表时间:
1999-11-01
影响因子:
2.2
通讯作者:
Taylor, TE
Taylor, TE
中科院分区:
医学4区
文献类型:
--
作者:
Lewallen, S;Harding, SP;Taylor, TE

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眼底病理在恶性疟原虫疟疾是常见的,并具有预后意义。我们已经共同努力,在几个人群中记录眼部特征。基于对马拉维、肯尼亚和冈比亚的735例散瞳患者进行的直接和间接检眼镜检查,我们确定了5种不同的临床特征(按频率顺序)包括视网膜变白、出血、独特的血管异常、视乳头水肿和棉絮斑。这些照片和描述,沿着提出了一个分级方案。
Ocular fundus pathology in Plasmodium falciparum malaria is common and has prognostic significance. We have made a collaborative effort to document the ocular features in several populations. Based on examination of 735 patients in Malawi, Kenya and The Gambia by direct and indirect ophthalmoscopy with dilated pupils, we have determined that the 5 distinct clinical features (in order of frequency) include retinal whitening, haemorrhages, unique Vessel abnormalities, papilloedema, and cotton wool spots. Photographs and descriptions of these are presented, along with a proposed grading scheme.