THE SLEEP THERAPIES OF DEPRESSION
THE SLEEP THERAPIES OF DEPRESSION
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DOI：
10.1016/0278-5846(83)90123-9
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发表时间：
1983-01-01
影响因子：
5.6
通讯作者：
GILLIN, JC
中科院分区：
文献类型：
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作者：
GILLIN, JC
1.1.本文综述了五种不同类型的有意识的睡眠-觉醒操作，据报道它们具有抗抑郁作用：完全睡眠剥夺，部分睡眠剥夺，睡眠期的相位提前和REM剥夺。完全剥夺睡眠的影响是有据可查的。在研究的852名抑郁症患者中，493人或57.9%在睡眠剥夺后得到改善。快速眼动剥夺程序的作用更慢，但更持久的临床价值比其他形式。在后半夜部分剥夺睡眠可能与完全剥夺睡眠一样好，并且更容易耐受。研究结果在心理，神经生理学，生物化学和时间生物学的角度进行审查。
1.1. This paper reviews five different types of deliberate sleep-wake manipulations which are reported to have antidepressant effects: total sleep deprivation, partial sleep deprivation, a phase advance of the sleep periods and REM deprivation.2.2. The effects of total sleep deprivation are best documented. Of 852 depressed patients studied, 493 or 57.9% improved following sleep deprivation.3.3. The REM deprivation procedure acts more slowly, but is of more lasting clinical value tha the other forms.4.4. Partial sleep deprivation during the second half of the night may be as good as total sleep deprivation and better tolerated.5.5. The findings are reviewed in terms of psychological, neurophysiological, biochemical and chronobiological perspectives.