Haematological and biochemical abnormalities in canine blood: frequency and associations in 1022 samples
Haematological and biochemical abnormalities in canine blood: frequency and associations in 1022 samples
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DOI：
10.1111/j.1748-5827.2004.tb00246.x
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发表时间：
2004-07-01
影响因子：
1.6
通讯作者：
Bertazzolo, W
中科院分区：
文献类型：
--
作者：
Comazzi, S;Pieralisi, C;Bertazzolo, W
在兽医实践中，向转诊实验室提交血液样本非常常见。内部参考范围应考虑适用于所用方法和仪器以及所考虑人群的已发表范围。本研究的目的是检查1022个连续犬血液检测的结果，分析异常的频率和主要关联，并比较不同年龄组的结果。将血液学和血清生化与内部范围和年龄组之间进行比较：小于1岁，1 - 8岁和大于8岁。幼龄犬的红细胞数量较低，血红蛋白浓度和红细胞压积值较低。他们还表现出更高的淋巴细胞数量和更高的磷浓度，71%的人表现出碱性磷酸酶升高。中性粒细胞增多症、高丙种球蛋白血症和低白蛋白血症在所有犬中均频繁发生，低白蛋白血症和高磷血症在尿毒症患者中常见。同时评价溶细胞酶和肝胆酶可更好地检测肝损伤，因为只有极低百分比的犬所有肝酶同时升高。
Submission of blood samples to referral laboratories is very common in veterinary practice. Internal reference ranges should take into account published ranges adapted to the methods and apparatus used and to the population under consideration. The aim of this study was to examine the results from 1022 consecutive canine blood tests, analysing the frequency and the main associations of abnormalities, and to compare the results in different age groups. Haemograms and serum biochemistry were compared with internal ranges and between age groups: younger than one year, one to eight years and older than eight years. Young dogs exhibited lower numbers of erythrocytes and lower values for haemoglobin concentration and packed cell volume. They also showed higher numbers of lymphocytes and higher concentrations of phosphorus and 71 per cent showed raised alkaline phosphatase. Neutrophilia, hypergammaglobulinaemia and hypoalbuminaemia occurred quite frequently in all dogs, and hypoalbuminaemia and hyperphosphataemia were commonly seen in uraemic patients. The simultaneous evaluation of cytolytic and hepatobiliary enzymes allowed better detection of liver damage, since only a very low percentage of dogs had simultaneous increases in all hepatic enzymes.