Citrinin Derivatives from the Marine-Derived Fungus Penicillium citrinum
Citrinin Derivatives from the Marine-Derived Fungus Penicillium citrinum
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来自海洋源性真菌柑橘青霉的柑橘素衍生物
DOI：
10.1248/cpb.59.515
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发表时间：
2011-04-01
影响因子：
1.7
通讯作者：
Zhang, Qi-Qing
中科院分区：
文献类型：
--
作者：
Chen, Li;Liu, Wei;Zhang, Qi-Qing
从柑橘青霉中分离出三种新的柑橘素衍生物：青霉醇 C、D 和 E (1-3)，以及两种已知化合物：柑橘素 (4) 和脱羧二氢柠檬酮 (5)。通过光谱方法和X射线衍射分析确定了它们的结构。化合物 1 和 3 对 HL-60 细胞系表现出弱细胞毒性。
Three new citrinin derivatives, penicitrinols C, D, and E (1-3), along with two known compounds, citrinin (4) and decarboxydihydrocitrinone (5), were isolated from Penicillium citrinum. Their structures were determined by spectroscopic methods and X-ray diffraction analysis. Compounds 1 and 3 demonstrated weak cytotoxicity against the HL-60 cell line.