High‐frequency oscillations in human brain
High‐frequency oscillations in human brain
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DOI：
10.1002/(sici)1098-1063(1999)9:2
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发表时间：
1999
期刊：
影响因子：
3.5
通讯作者：
A. Bragin;J. Engel;C. Wilson;I. Fried;G. Buzsáki
中科院分区：
文献类型：
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作者：
A. Bragin;J. Engel;C. Wilson;I. Fried;G. Buzsáki
纹波是最近在大鼠海马和内嗅皮层中记录的100-200 Hz短持续振荡场电位。它们反映了锥体细胞索马体上的快速IPSPs，其发生在主细胞和中间神经元网络的同步传入兴奋期间。我们现在描述两种相似类型的高频场振荡记录从内侧颞叶癫痫患者的内嗅皮层和海马。第一种类型似乎是人类相当于老鼠的正常波纹。第二种，我们称之为快速纹波（FR），在250-500 Hz的频率范围内。FR被发现在致痫区域，并可能反映病理超同步群体棘波爆裂锥体细胞。Hippocampus 1999;9：137-142.© 1999 Wiley‐利斯公司
Ripples are 100–200 Hz short‐duration oscillatory field potentials that have recently been recorded in rat hippocampus and entorhinal cortex. They reflect fast IPSPs on the soma of pyramidal cells, which occur during synchronous afferent excitation of principal cells and interneuron networks. We now describe two similar types of high‐frequency field oscillations recorded from the entorhinal cortex and hippocampus of patients with mesial temporal lobe epilepsy. The first type appears be the human equivalent of normal ripples in the rat. The second, which we have termed fast ripples (FR), are in the frequency range of 250–500 Hz. FR are found in the epileptogenic region and may reflect pathological hypersynchronous population spikes of bursting pyramidal cells. Hippocampus 1999;9:137–142. © 1999 Wiley‐Liss, Inc.