Microwave-Assisted Multicomponent Synthesis of Heterocycles
Microwave-Assisted Multicomponent Synthesis of Heterocycles
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DOI：
10.2174/138527211793979817
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发表时间：
2011-01-01
影响因子：
2.6
通讯作者：
Orru, Romano V. A.
中科院分区：
文献类型：
--
作者：
Kruithof, Art;Ruijter, Eelco;Orru, Romano V. A.
多组分反应是合成多种杂环化合物的重要工具。正如在有机化学的许多领域一样，微波辐射在多组分化学中正迅速取代传统的加热方法。本文综述了近年来微波在多组分杂环化合物合成中的应用。在可能的情况下，微波辅助反应的产率和化学，区域和立体选择性进行了比较与使用常规加热。
Multicomponent reactions are valuable tools for the generation of diverse heterocycles. As in many fields or organic chemistry, microwave irradiation is rapidly replacing conventional heating methods in multicomponent chemistry. In this review, we present an overview of recent applications of the use of microwaves in multicomponent heterocycle synthesis. Where possible, the yield and chemo-, regio- and stereoselectivity of microwave-assisted reactions are compared with those using conventional heating.