Highly Conjugative pMG1-Like Plasmids Carrying Tn1546-Like Transposons That Encode Vancomycin Resistance in Enterococcus faecium

Highly Conjugative pMG1-Like Plasmids Carrying Tn1546-Like Transposons That Encode Vancomycin Resistance in Enterococcus faecium
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DOI:
10.1128/jb.185.23.7024-7028.2003
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发表时间:
2003-12
影响因子:
3.2
通讯作者:
H. Tomita;K. Tanimoto;S. Hayakawa;Kyoko Morinaga;Kohji Ezaki;Hisaji Oshima;Y. Ike
H. Tomita;K. Tanimoto;S. Hayakawa;Kyoko Morinaga;Kohji Ezaki;Hisaji Oshima;Y. Ike
中科院分区:
生物学3区
文献类型:
--
作者:
H. Tomita;K. Tanimoto;S. Hayakawa;Kyoko Morinaga;Kohji Ezaki;Hisaji Oshima;Y. Ike

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摘要对12株VanA型万古霉素耐药肠球菌,包括10株屎肠球菌和2株鸟肠球菌进行了详细的检测。从3株不同的大肠杆菌中分离到万古霉素抗性接合质粒pHTα(65.9kbp)、pHTβ(63.7kbp)和pHTγ(66.5kbp)。粪菌菌株在肉汤交配过程中肠球菌菌株之间的质粒转移效率很高,并与pMG 1(Gmr; 65.1 kb)同源。
ABSTRACT A total of 12 VanA-type vancomycin-resistant enterococci, consisting of 10 Enterococcus faecium isolates and two Enterococcus avium isolates, were examined in detail. The vancomycin resistance conjugative plasmids pHTα (65.9 kbp), pHTβ (63.7 kbp), and pHTγ (66.5 kbp) were isolated from each of three different E. faecium strains. The plasmids transferred highly efficiently between enterococcus strains during broth mating and were homologous with pMG1 (Gmr; 65.1 kb).