Cell renewal and ground substance formation in replanted cat teeth.
Cell renewal and ground substance formation in replanted cat teeth.
复制标题
重新种植的猫牙中的细胞更新和基质形成。
DOI：
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发表时间：
1990
影响因子：
2
通讯作者：
K. Heyeraas
中科院分区：
文献类型：
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作者：
I. Kvinnsland;K. Heyeraas
应用~3H-胸腺嘧啶核苷和~(35)S-硫酸盐脉冲标记、放射自显影和常规组织学方法，对47颗猫切牙再植后4、10、30、60天牙髓愈合的细胞动力学模式进行了研究。对照牙标记指数小于0.05%。再植后4d，根尖髓细胞即可形成基质和细胞增殖，标记指数为7%，10d内可达43%。术后牙髓细胞间隙逐渐恢复和重组。最大细胞密度在30天后达到，与对照组相比平均降低了60%。60d后，所有牙髓区的组织重组接近完成，标记指数降至2.5%。在某些情况下，颈髓区域的内部吸收对良好的愈合有负面影响。本研究表明，再植牙的牙髓愈合在细胞动力学和组织学变化方面遵循一致的基本模式。因此，再植的牙齿似乎是研究结缔组织愈合和修复的合适模型。
The cellular dynamic pattern of pulpal healing 4, 10, 30, and 60 days after replantation of 47 apicoectomized cat incisors was studied after pulse labeling with 3H-thymidine and 35S-sulfate, autoradiography, and routine histology. In the control teeth the labeling index was less than 0.05%. The apical pulpal cells were capable of ground substance formation and cell proliferation already 4 days after replantation, with a labeling index of 7%, which increased up to 43% within 10 days. A gradual postoperative restitution and reorganization within the pulpal cellular compartment was seen. The maximum cell density, reached after 30 days, was reduced to on average 60% compared with the controls. The tissue reorganization was near completion within all pulpal zones after 60 days, and the labeling index was reduced to 2.5%. In some instances internal resorption in cervical pulpal areas negatively influenced the favorable healing. The present study shows that the pulpal healing in replanted teeth follows a consistent basic pattern in cellular dynamics and in histologic changes. The replanted tooth thus seems to be a suitable model for studies of healing and repair in connective tissues.