Structural and sequence-based classification of glycoside hydrolases
Structural and sequence-based classification of glycoside hydrolases
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DOI：
10.1016/s0959-440x(97)80072-3
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发表时间：
1997-10-01
影响因子：
6.8
通讯作者：
Davies, G
中科院分区：
文献类型：
--
作者：
Henrissat, B;Davies, G
寡糖和多糖的多样性为这些碳水化合物提供了丰富的生物学功能。水解这些化合物的酶，糖苷水解酶，因此介导了丰富的生物功能。糖苷水解酶属于许多基于序列的家族。近年来对这些酶家族的分析，以及大量三维结构的研究，为这些酶的结构、功能和催化机制提供了详细的信息。寡糖和多糖的多样性为这些糖类提供了丰富的生物学功能。水解这些化合物的酶，糖苷水解酶，因此介导了丰富的生物功能。糖苷水解酶属于许多基于序列的家族。最近对这些家族的分析，加上3D结构的迅速发展，为这些酶的结构，功能和催化机制提供了详细的见解。(C)Current Biology Ltd ISSN 0959-440X
The diversity of oligo-and polysaccharides provides an abundance of biological roles for these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases, therefore mediate a wealth of biological functions. Glycoside hydrolases fall into a number of sequence-based families. The recent analysis of these families, coupled with the burgeoning number of 3D structures, provides a detailed insight into the structure, function and catalytic mechanism of these enzymes.The diversity of oligo-and polysaccharides provides an abundance of biological roles for these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases, therefore mediate a wealth of biological functions. Glycoside hydrolases fall into a number of sequence-based families. The recent analysis of these families, coupled with the burgeoning number of 3D structures, provides a detailed insight into the structure, function and catalytic mechanism of these enzymes. (C) Current Biology Ltd ISSN 0959-440X