Therapeutic plasma exchange in renal diseases.
Therapeutic plasma exchange in renal diseases.
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发表时间：
1996-03
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通讯作者：
F. Madoré;J. Lazarus;H. Brady
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作者：
F. Madoré;J. Lazarus;H. Brady
血浆置换已被广泛用于治疗多种肾脏疾病超过25年。本文综述了血浆置换治疗原发性和继发性肾小球肾炎、血栓性血小板减少性紫癜和溶血性尿毒症综合征、骨髓瘤铸造肾病和同种异体移植排斥反应的科学依据。总结了评价其疗效的临床研究，特别强调了随机对照试验的结果，如果有的话。对于有证据支持其使用的疾病，提出了共识血浆交换方案。
Plasma exchange has been used extensively for over 2 1/2 decades to treat a variety of renal diseases. In this article, the scientific rationale for therapeutic plasma exchange in primary and secondary glomerulonephritis, thrombotic thrombocytopenic purpura and hemolytic uremic syndrome, myeloma cast nephropathy, and allograft rejection are reviewed. The clinical studies that evaluate its efficacy are summarized, with special emphasis on the results of randomized controlled trials, when available. Consensus plasma exchange regimens are presented for diseases in which there is evidence to support its use.