MICROSCOPIC STUDIES OF EFFECT OF EPINEPHRINE ON ISOLATED FAT CELLS OF RAT EPIDIDYMAL FAT PADS
MICROSCOPIC STUDIES OF EFFECT OF EPINEPHRINE ON ISOLATED FAT CELLS OF RAT EPIDIDYMAL FAT PADS
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DOI：
10.1016/0014-4827(67)90417-x
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发表时间：
1967-01-01
影响因子：
3.7
通讯作者：
MURTHY, SK
中科院分区：
文献类型：
--
作者：
MURTHY, SK
从喂养良好的大鼠附睾脂肪垫中分离出的脂肪细胞含有很少的富含脂质的颗粒。与肾上腺素一起孵育后，这些颗粒的数量在体外增加。这些富含脂质的颗粒仅当它们积极参与将非酯化脂肪酸释放到培养基中时才出现在细胞中。这些经肾上腺素处理的细胞的电子显微照片显示它们是富含脂质且具有光滑细胞膜的细胞。这些小体主要由大块脂质响应肾上腺素的刺激而形成，并且可能作为将脂质从大块脂肪运输到细胞质中脂肪酶中心的载体。
Fat cells isolated from epididymal fat pads of well-fed rats contain very few lipid-rich particles. The numbers of these particles increase in vitro following incubation with epinephrine. These lipid-rich particles appear in the cells only when they are actively engaged in the release of non-esterified fatty acid into the medium. Electron micrographs of these epinephrine treated cells show them to be lipid-rich bodies with a smooth membrane. These bodies are mostly formed from the bulk lipid in response to the stimulus given by epinephrine and probably serve as vehicles for the transport of lipid from the bulk fat to the centers of lipase in the cytoplasm.