Parasite Microbiome Project: Systematic Investigation of Microbiome Dynamics within and across Parasite-Host Interactions.
Parasite Microbiome Project: Systematic Investigation of Microbiome Dynamics within and across Parasite-Host Interactions.
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DOI：
10.1128/msystems.00050-17
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发表时间：
2017-07
期刊：
影响因子：
6.4
通讯作者：
Rosario K
中科院分区：
文献类型：
--
作者：
Dheilly NM;Bolnick D;Bordenstein S;Brindley PJ;Figuères C;Holmes EC;Martínez Martínez J;Phillips AJ;Poulin R;Rosario K
了解微生物组如何影响宿主抗性，寄生虫毒力和寄生虫相关疾病需要寄生虫学家，微生物生态学家，病毒学家和免疫学家之间的合作努力。我们在此提出寄生虫微生物组计划，将具有互补专业知识的研究人员聚集在一起，研究微生物在宿主-寄生虫相互作用中的作用。了解微生物组如何影响宿主抗性，寄生虫毒力和寄生虫相关疾病需要寄生虫学家，微生物生态学家，病毒学家和免疫学家之间的合作努力。我们在此提出寄生虫微生物组计划，将具有互补专业知识的研究人员聚集在一起，研究微生物在宿主-寄生虫相互作用中的作用。来自寄生虫微生物组项目的数据将有助于确定驱动寄生虫和受感染宿主微生物组变异的机制，以及这种变异如何与寄生虫的生态和进化及其疾病结果相关。这是一个号召，以防止分散的研究工作，鼓励实验方法的最佳实践，并允许跨模型系统进行可靠的比较分析。这也是对基金会和国家资助机构的邀请，以推动寄生虫学领域进入微生物组/宏基因组时代。
Understanding how microbiomes affect host resistance, parasite virulence, and parasite-associated diseases requires a collaborative effort between parasitologists, microbial ecologists, virologists, and immunologists. We hereby propose the Parasite Microbiome Project to bring together researchers with complementary expertise and to study the role of microbes in host-parasite interactions. Understanding how microbiomes affect host resistance, parasite virulence, and parasite-associated diseases requires a collaborative effort between parasitologists, microbial ecologists, virologists, and immunologists. We hereby propose the Parasite Microbiome Project to bring together researchers with complementary expertise and to study the role of microbes in host-parasite interactions. Data from the Parasite Microbiome Project will help identify the mechanisms driving microbiome variation in parasites and infected hosts and how that variation is associated with the ecology and evolution of parasites and their disease outcomes. This is a call to arms to prevent fragmented research endeavors, encourage best practices in experimental approaches, and allow reliable comparative analyses across model systems. It is also an invitation to foundations and national funding agencies to propel the field of parasitology into the microbiome/metagenomic era.