Increases in manic symptoms after life events involving goal attainment
Increases in manic symptoms after life events involving goal attainment
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DOI：
10.1037/0021-843x.109.4.721
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发表时间：
2000-11-01
影响因子：
4.6
通讯作者：
Keitner, G
中科院分区：
文献类型：
--
作者：
Johnson, SL;Sandrow, D;Keitner, G
双相情感障碍已被概念化为行为激活系统（BAS）（一种调节目标导向活动的大脑系统）失调的结果。在BAS模型的基础上，作者假设涉及目标实现的生活事件会促进双相情感障碍患者的躁狂症状。作者每月对43名双相I型患者进行标准化症状严重程度评估（改良汉密尔顿抑郁量表和Bech-Rafaelsen躁狂发作量表）。使用生活事件和困难量表的目标达成和积极性量表评估生活事件。就像假设的那样。躁狂症状在目标达成事件后的2个月内增加，但抑郁症状在目标达成事件后没有改变。这些结果与最近的一系列极性特异性研究结果一致。
Bipolar disorder has been conceptualized as an outcome of dysregulation in the behavioral activation system (BAS), a brain system that regulates goal-directed activity. On the basis of the BAS model, the authors hypothesized that life events involving goal attainment would promote manic symptoms in bipolar individuals. The authors followed 43 bipolar I individuals monthly with standardized symptom severity assessments (the Modified Hamilton Rating Scale for Depression and the Bech-Rafaelsen Mania Raring Scale). Life events were assessed using the Goal Attainment and Positivity scales of the Life Events and Difficulties Schedule. As hypothesized. manic symptoms increased in the 2 months following goal-attainment events, but depressed symptoms were not changed following goal-attainment events. These results are congruent with a series of recent polarity-specific findings.