Efficacy of Body Wash and Povidone-Iodine in Skin Preparation in Reducing Surgical Site Infections After Hypospadias Repair Among Adolescents: A Prospective Cohort Study With Retrospective Controls
Efficacy of Body Wash and Povidone-Iodine in Skin Preparation in Reducing Surgical Site Infections After Hypospadias Repair Among Adolescents: A Prospective Cohort Study With Retrospective Controls
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DOI：
10.1089/sur.2023.268
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发表时间：
2023-11-01
影响因子：
2
通讯作者：
Wei，Guang-Hui
中科院分区：
文献类型：
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作者：
Ye，Zi-Han;Wang，Chong;Wei，Guang-Hui
背景：尿道下裂修复术后发生的手术部位感染（SSI）经常导致切口愈合并发症，尤其是在青春期。本研究旨在评估在青少年尿道下裂修复术前48小时内使用沐浴露和聚维酮碘进行每日两次术前皮肤准备对感染率的影响。患者和方法：前瞻性招募包括2015年1月至2021年1月接受尿道下裂修复术的坦纳3至5期患者。实验组包括在手术前48小时内每天两次用沐浴露和聚维酮碘进行皮肤准备的患者。外科医生选择0.5%或5%聚维酮碘进行皮肤准备。对照组包括在过去五年中进行的尿道下裂修复的回顾性队列，其中患者在术前使用沐浴液进行晚间淋浴。并发症收集了超过6个月的随访periods.Results：该研究包括90例患者在0.5%聚维酮碘组，92例患者在5%聚维酮碘组，和84例患者在对照组。在SSI（p = 0.030）和尿道瘘（p = 0.019）方面观察到组间差异。在事后检验中，只有5%的聚维酮碘组表现出减少SSI（p = 0.009）和尿道瘘（p = 0.005）的发病率相比，对照组Conclusions：使用沐浴露和5%的聚维酮碘皮肤准备与减少SSI和尿道瘘的发病率尿道下裂修复后的青少年，可以被认为是改善结果。
Background:Surgical site infections (SSIs) that occur after hypospadias repair frequently result in incision healing complications, especially during puberty. This study aimed to evaluate the efficacy of twice-daily pre-operative skin preparation using body wash and povidone-iodine within 48 hours before hypospadias repair with regard to infection rates in adolescents.Patients and Methods:Prospective recruitment included patients in Tanner stages 3 to 5 undergoing hypospadias repair from January 2015 to January 2021. The experimental group comprised patients who performed twice-daily skin preparation with body wash and povidone-iodine within 48 hours before surgery. Surgeons selected either 0.5% or 5% povidone-iodine for skin preparation. The control group comprised a retrospective cohort of hypospadias repair conducted in the preceding five years, where patients performed pre-surgery evening showers using a body wash. Complications were collected over a six-month follow-up period.Results:The study included 90 patients in the 0.5% povidone-iodine group, 92 patients in the 5% povidone-iodine group, and 84 patients in the control group. Differences were observed among the groups in terms of SSI (p = 0.030) and urethral fistula (p = 0.019). In post hoc tests, only the 5% povidone-iodine group demonstrated a diminished incidence of SSI (p = 0.009) and urethral fistula (p = 0.005) in comparison to the control group.Conclusions:Using body wash and 5% povidone-iodine for skin preparation was associated with a reduction in the incidence of SSI and urethral fistula following hypospadias repair in adolescents and may be considered to improve outcomes.