Antioxidant protective effects of lactitol against endotoxemia in patients with chronic viral hepatitis
Antioxidant protective effects of lactitol against endotoxemia in patients with chronic viral hepatitis
复制标题
乳糖醇对慢性病毒性肝炎患者内毒素血症的抗氧化保护作用
DOI：
10.3892/mmr.2012.1188
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发表时间：
2013-02-01
影响因子：
3.4
通讯作者：
Li, Lanjuan
中科院分区：
文献类型：
--
作者：
Chen, Chunlei;Yu, Xiuli;Li, Lanjuan
尽管抗病毒药物在临床上得到了广泛的应用，但仍不能完全阻止进展为肝硬变和肝细胞癌。本研究的目的是确定乳糖醇治疗慢性病毒性肝炎合并内毒素血症的疗效。根据血浆内毒素水平将94例慢性病毒性肝炎患者分为内毒素血症组(45 ng/L，n=60)和非内毒素血症组(n=60)。
Although antiviral drugs are widely used in the clinic, progression to liver cirrhosis and hepatocellular carcinoma cannot yet be entirely prevented. The aim of this study was to determine the effects of lactitol in chronic viral hepatitis patients with endotoxemia. Ninety-four patients with chronic viral hepatitis were separated into two groups based on plasma endotoxin levels: one group with endotoxemia (>= 45 ng/l, n=60) and one group without endotoxemia (