Acral lentiginous melanoma: incidence and survival patterns in the United States, 1986-2005.
Acral lentiginous melanoma: incidence and survival patterns in the United States, 1986-2005.
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DOI：
10.1001/archdermatol.2008.609
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发表时间：
2009-04
影响因子：
--
通讯作者：
Tucker, Margaret A.
中科院分区：
文献类型：
--
作者：
Bradford, Porcia T.;Goldstein, Alisa M.;McMaster, Mary L.;Tucker, Margaret A.
目的：研究美国肢端黄斑性黑色素瘤（ALM）的发病率和生存模式。基于人群的登记研究。我们使用国家癌症研究所的监测、流行病学和最终结果（SEER）项目来评估从1986年到2005年17个基于人群的癌症登记处的数据。报告了1413例组织学确诊的ALM病例。ALM患者的发病率和生存模式。经年龄调整的ALM总体发病率为1.8 /百万人-年。在所有黑色素瘤亚型中，黑人的ALM比例最高（36%）。ALM的5年和10年黑色素瘤特异性生存率分别为80.3%和67.5%，低于所有皮肤恶性黑色素瘤（CMM）的91.3%和87.5%,（p<0.001）。ALM 5年和10年黑色素瘤特异性生存率在非西班牙裔白人中最高（82.6%和69.4%），在黑人中居中（77.2%和71.5%），在西班牙裔白人（72.8%和57.3%）和亚洲/太平洋岛民中最低（70.2%和54.1%）。在性别和不同种族中，ALM厚度和分期与生存率相关。基于人群的数据显示，ALM是一种罕见的黑色素瘤亚型，尽管其在所有黑色素瘤中的比例在有色人种中较高。总体而言，ALM的预后比CMM差。西班牙裔白人和亚洲/太平洋岛民的生存率比其他群体更差，肿瘤厚度增加和出现时的晚期等因素是最可能的解释。
To examine incidence and survival patterns of acral lentiginous melanoma (ALM) in the United States. Population-based registry study. We used the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute to evaluate data from 17 population-based cancer registries from 1986 to 2005. 1413 histologically confirmed cases of ALM were reported. Incidence and survival patterns of patients with ALM. The age-adjusted incidence rate of ALM overall was 1.8 per million person-years. The proportion of ALM among all melanoma subtypes was greatest in Blacks (36%). ALM had five- and ten-year melanoma-specific survival rates of 80.3% and 67.5%, respectively, which were less than for all cutaneous malignant melanoma (CMM) overall 91.3% and 87.5%, (p<0.001). ALM five- and ten-year melanoma-specific survival rates were highest in Non-Hispanic Whites (82.6% and 69.4%), intermediate in Blacks (77.2% and 71.5%), and lowest in Hispanic Whites (72.8% and 57.3%) and Asian/Pacific Islanders (70.2% and 54.1%). ALM thickness and stage correlated with survival in gender and the different racial groups. Population-based data showed that ALM is a rare melanoma subtype, although its proportion amongst all melanoma is higher in people of color. ALM is associated with a worse prognosis than CMM overall. Hispanic Whites and Asian/Pacific Islanders have worse survival rates than other groups, and factors such as increased tumor thickness and more advanced stage at presentation are the most likely explanations.
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影响因子：
--
作者：
Demierre, MF;Chung, C;Geller, AC
通讯作者：
Geller, AC
影响因子：
45.3
作者：
Gimotty, PA;Botbyl, J;Guerry, D
通讯作者：
Guerry, D
影响因子：
9
作者：
BRESLOW, A
通讯作者：
BRESLOW, A
影响因子：
10.3
作者：
Kuchelmeister, C;Schaumburg-Lever, G;Garbe, C
通讯作者：
Garbe, C
影响因子：
--
作者：
COLEMAN, WP;LORIA, PR;KREMENTZ, ET
通讯作者：
KREMENTZ, ET