Fluorine analysis of human enamel around fluoride-containing materials under different pH-cycling by μ-PIGE/PIXE system
Fluorine analysis of human enamel around fluoride-containing materials under different pH-cycling by μ-PIGE/PIXE system
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DOI：
10.1016/j.nimb.2011.02.042
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发表时间：
2011-10-15
影响因子：
1.3
通讯作者：
Oikawa, S.
中科院分区：
文献类型：
--
作者：
Komatsu, H.;Yamamoto, H.;Oikawa, S.
含氟材料的防龋效果可能取决于个体患龋风险。制备了两组pH循环的脱矿和再矿化溶液，分别模拟低龋和高龋风险。本研究的目的是使用空气中的mu-PIGE/PIXE系统来测定在不同pH循环条件下，人牙釉质中的氟（F）吸收。本研究使用含氟玻璃离子粘固剂（Fuji IXGP FAST CAPSULE（FN））和复合树脂（BEAUTIFIL II with FLUORO BOND SHAKE ONE（BS））。pH循环（pH 6.8-4.5）进行5周。pH循环后，使用横向显微放射照相（TMR）分析龋齿进展。用PIGE/PIXE系统检测龋损区氟、钙的分布。从TMR分析，有两种pH循环之间的龋风险的差异。虽然BS和FN的防龋效果在低风险下得到证实，但仅FN在高风险下得到证实。根据对病变外部200 μ m的氟吸收的分析，我们得出结论，pH循环溶液之间没有显着差异。然而，我们发现不同的氟浓度的牙釉质中的两个FCM。FN高风险下龋齿进展的减少表明，在较高的龋齿风险下，需要从材料中提供足够量的氟。结果表明，FCM的防龋效果取决于患龋风险。在不同pH循环条件下的牙齿氟分析提供了根据龋齿风险评估含氟材料的防龋效果的信息。(C)2011 Elsevier B. V.保留所有权利。
The caries preventive effect of fluoride-containing materials (FCMs) might depend on the caries risk of the individuals. Two pairs of demineralizing and remineralizing solutions of pH-cycling were prepared for simulating low and high caries risk. The purpose of this study was to determine fluorine (F) uptake into human enamel around FCMs under different pH-cycling using the in-air mu-PIGE/PIXE system. Fluoride-containing glass ionomer cement (Fuji IXGP FAST CAPSULE (FN)), and composite resin (BEAUTIFIL II with FLUORO BOND SHAKE ONE (BS)) were used in this study. The pH-cycling (pH 6.8-4.5) was carried out for 5 weeks. After pH-cycling, the caries progression was analyzed using transverse micro-radiography (TMR). The fluorine and calcium distributions in the carious lesion in each specimen were evaluated using the PIGE/PIXE system. From TMR analysis, there was a difference in caries risk between the two kinds of pH-cycling. Although the caries preventive effect of BS and FN was confirmed at low risk, the effect at high risk was confirmed for FN only. From the analysis of the fluorine uptake in the outer 200 mu m of the lesion we concluded that there was no significant difference between the pH-cycling solutions. However, we found different fluorine concentrations in the enamel for the two FCMs. The decreased caries progression under high risk for FN indicated that an adequate amount of fluorine supplied from the material is required at higher caries risk. It was confirmed that the caries preventive effect of FCM depends on the caries risk. The fluorine analysis of teeth under various pH-cycling conditions gives information to evaluate the caries preventive effect of fluoride-containing materials according to the caries risk. (C) 2011 Elsevier B.V. All rights reserved.