Prevalence, awareness and risk factors of hypertension in a large cohort of Iranian adult population.
Prevalence, awareness and risk factors of hypertension in a large cohort of Iranian adult population.
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DOI：
10.1097/hjh.0b013e3283613053
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发表时间：
2013-07
影响因子：
4.9
通讯作者：
Malekzadeh R
中科院分区：
文献类型：
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作者：
Malekzadeh MM;Etemadi A;Kamangar F;Khademi H;Golozar A;Islami F;Pourshams A;Poustchi H;Navabakhsh B;Naemi M;Pharoah PD;Abnet CC;Brennan P;Boffetta P;Dawsey SM;Esteghamati A;Malekzadeh R
不同地理位置和种族群体的高血压患病率和认识及其相关性存在很大差异。我们对 Golestan 队列研究 (GCS) 的数据进行了横断面分析。这项研究的入组时间为 2004 年至 2008 年，包括来自伊朗东北部古勒斯坦省的 50,045 名健康受试者。高血压的定义为收缩压（SBP）≥140、舒张压（DBP）≥90、既往高血压诊断或使用抗高血压药物。通过对性别、年龄、体重指数、居住地、识字率、种族、体力活动、吸烟、红茶和绿茶消费以及财富评分进行调整的逻辑回归分析高血压及其认知的潜在相关性。在所有队列参与者中，21,350 人（42.7%）患有高血压。根据 2001 年世界卫生组织标准世界人口，高血压的年龄标准化患病率为 41.8%（95%CI：38.3%–45.2%）。高血压与女性性别、体重指数增加、土库曼民族和缺乏体力活动直接相关，与喝红茶和财富得分呈负相关。在高血压患者中，46.2%的人了解自己的疾病，17.6%的人正在接受抗高血压药物治疗，32.1%的治疗者高血压得到控制。女性、老年人、超重和肥胖人群以及财富得分较高的人群对高血压的认识更高。高血压在伊朗农村地区非常普遍，许多受影响的人并不知道自己患有这种疾病，而且抗高血压药物的控制率很低。建议提高高血压意识和获得卫生服务的机会，特别是在弱势居民中。
There is considerable variation in hypertension prevalence and awareness, and their correlates, across different geographic locations and ethnic groups. We performed this cross-sectional analysis on data from the Golestan Cohort Study (GCS). Enrollment in this study occurred in 2004–2008, and included 50,045 healthy subjects from Golestan Province in northeastern Iran. Hypertension was defined as a systolic blood pressure (SBP) ≥140, a diastolic blood pressure (DBP) ≥90, a prior diagnosis of hypertension, or the use of antihypertensive drugs. Potential correlates of hypertension and its awareness were analyzed by logistic regression adjusted for sex, age, BMI, place of residence, literacy, ethnicity, physical activity, smoking, black and green tea consumption and wealth score. Of the total cohort participants, 21,350 (42.7%) were hypertensive. Age-standardized prevalence of hypertension, using the 2001 WHO standard world population, was 41.8% (95%CI: 38.3%–45.2%). Hypertension was directly associated with female sex, increased BMI, Turkmen ethnicity, and lack of physical activity, and inversely associated with drinking black tea and wealth score. Among hypertensive subjects, 46.2% were aware of their disease, 17.6% were receiving antihypertensive medication, and 32.1% of the treated subjects had controlled hypertension. Hypertension awareness was greater among women, the elderly, overweight and obese subjects, and those with a higher wealth score. Hypertension is highly prevalent in rural Iran, many of the affected individuals are unaware of their disease, and the rate of control by antihypertensive medications is low. Increasing hypertension awareness and access to health services, especially among less privileged residents are recommended.