Impact of micronutrient deficiencies on growth: The stunting syndrome
Impact of micronutrient deficiencies on growth: The stunting syndrome
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DOI：
10.1159/000066397
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发表时间：
2002-01-01
影响因子：
3.9
通讯作者：
Ferrari, M
中科院分区：
文献类型：
--
作者：
Branca, F;Ferrari, M
发育迟缓是一个可以影响儿童发育的过程，从怀孕的早期阶段一直到三、四年，此时母亲和孩子的营养是生长的基本决定因素。未能满足微量营养素的需求、具有挑战性的环境和护理提供不足，都是造成这种影响近2亿5岁以下儿童的疾病的因素。营养侮辱的时间和持续时间导致不同的生理后果。然而，生长迟缓只是复杂综合征的一个特征，包括发育迟缓、免疫功能受损、认知功能下降和代谢紊乱，导致肥胖和高血压的预期风险增加。通过在生命周期的所有阶段采取干预措施，预防是可能的，主要包括促进纯母乳喂养直到6个月大，并提供补充食品和具有足够微量营养素密度的家庭食品。治疗是可能的，至少在5岁之前，并且可以导致所有症状的逆转，尽管需要进一步的研究来澄清是否加速生长速度也可能导致代谢综合征的风险增加。版权所有(C) 2002 S. Karger AG，巴塞尔。
Stunting is a process that can affect the development of a child from the early stages of conception and until the third or fourth year of life, when the nutrition ofthe mother and the child are essential determinants of growth. Failure to meet micronutrient requirements, a challenging environment and the inadequate provision of care, are all factors responsible for this condition that affects almost 200 million children under 5 years of age. The timing and duration of the nutritional insult leads to different physiological consequences. Growth retardation is however just one feature of a complex syndrome including developmental delay, impaired immune function, reduced cognitive function and metabolic disturbances leading to increased prospective risk of obesity and hypertension. Prevention is possible by undertaking interventions at all stages of the life cycle, and mainly involves the promotion of exclusive breast-feeding until the age of 6 months and the provision of complementary foods and family foods with adequate micronutrient density. Treatment is possible, at least until the age of 5, and can lead to reversal of all the symptoms, although further research is required to clarify whether accelerating growth velocity might also lead to an increased risk of metabolic syndrome. Copyright (C) 2002 S. Karger AG, Basel.