DNA cleavage by an alpha, 3-dehydrotoluene precursor conjugated to a minor groove binding element.

DNA cleavage by an alpha, 3-dehydrotoluene precursor conjugated to a minor groove binding element.
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DNA 通过与小沟结合元件缀合的 α, 3-脱氢甲苯前体进行切割。

DOI:
10.1021/bc9600170
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发表时间:
1996
期刊:
Bioconjugate chemistry.
影响因子:
--
通讯作者:
Parrish,CA
Parrish,CA
中科院分区:
--
文献类型:
--
作者:
Myers,AG;Parrish,CA

文献摘要

相似文献

The (Z)-allene-ene-yne10, a precursor to a reactive α,3-dehydrotoluene biradical, was covalently linked to a minor groove binding element, and the resultant conjugate (9) was shown to bind and cleave DNA with sequence selectivity.