Prevalence of osteoporosis and osteopenia in advanced chronic obstructive pulmonary disease patients
Prevalence of osteoporosis and osteopenia in advanced chronic obstructive pulmonary disease patients
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DOI：
10.4103/0970-2113.83974
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发表时间：
2011-07-01
期刊：
影响因子：
1.6
通讯作者：
Bardhan, Sujan
中科院分区：
文献类型：
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作者：
Bhattacharyya, Parthasarathi;Paul, Rantu;Bardhan, Sujan
背景：骨密度（BMD）降低是慢性阻塞性肺疾病（COPD）中一种已知且确定的现象。然而，没有关于印度COPD患者骨质疏松/骨质减少的数据。目的：了解诊断为COPD的OPD患者骨质疏松/骨质减少的程度和频率。材料和方法：随机选择37例COPD患者，在肺OPD中使用市售超声骨密度仪（HOLOGIC SAHARA）评估骨密度。还指出了降低骨密度的一些辅助因素。结果：在37例COPD（均属于GOLD III/IV类）患者中，10例（27%）患者骨密度正常，27例（73%）患者出现骨质减少/骨质疏松[分别为19例（51.35%）和8例（21.62%）存在骨质减少和骨质疏松]。结论：骨质疏松和骨质减少的发生率在我们的晚期COPD人群中非常高（73%）。这些数据表明有必要对这个问题进行进一步深入的研究。
Background: Reduction of bone mineral density (BMD) is a known and established phenomenon in chronic obstructive pulmonary disease (COPD). However, there have been no data regarding osteoporosis/osteopenia in COPD patients in India. Aim: To look for the degree and frequency of osteoporosis/osteopenia in our OPD patients being diagnosed as COPD. Materials and Methods: Thirty-seven randomly selected patients with COPD were assessed for BMD with commercially available ultrasound bone densitometer (HOLOGIC SAHARA) in a pulmonary OPD. Some cofactors for reduced BMD were also noted. Results: Out of the 37 COPD (all belonging to the GOLD III/IV category) patients studied, the BMD was found to be normal in 10 (27%) patients, while 27 (73%) patients were found to have osteopenia/osteoporosis [19 (51.35%) and 8 (21.62%) patients having osteopenia and osteoporosis, respectively]. Conclusion: Frequency of osteoporosis and osteopenia was found to be very high (73%) in our population of advanced COPD. The data suggest a need for further in-depth study regarding the issue.