Mapping Surface Variability of the Central Sulcus in Musicians
Mapping Surface Variability of the Central Sulcus in Musicians
复制标题
绘制音乐家中央沟的表面变化
DOI：
10.1093/cercor/bhp074
复制
发表时间：
2010-01-01
期刊：
影响因子：
3.7
通讯作者：
He, Yong
中科院分区：
文献类型：
--
作者：
Li, Shuyu;Han, Ying;He, Yong
我们采用一种基于脑沟几何的方法来研究音乐家（钢琴家）中央脑沟（CS）的形态学。首先从41名右撇子受试者（20名音乐家和21名对照组）的高分辨率磁共振（MR）图像中手动勾画出CS的前后壁，然后进行表面重建和参数化程序，以确保受试者之间表面位置的解剖一致性。测量导管内长度、表面积和局部变异性。两组间管内长度及前后壁表面积均无显著差异。然而，我们观察到控制组有明显的左大于右的不对称性，而音乐家组的这种不对称性有所减少。重要的是，我们发现，与对照组相比，音乐家在右CS的中部（即躯体手区）和左CS的下部显示出更大的局部变异性。进一步的分析表明，右CS中间部分的变异性与开始音乐训练的年龄之间存在显著的负相关。我们的研究结果表明，音乐家可能与长期运动技能训练后CS三维形态的可塑性变化有关。
We employed a sulcal geometry-based approach to investigate the morphology of the central sulcus (CS) in musicians (pianists). The anterior and posterior walls of the CS were first manually outlined from high-resolution magnetic resonance (MR) images of 41 right-handed subjects (20 musicians and 21 controls), followed by a surface reconstruction and parameterization procedure to ensure the anatomical correspondence of surface locations across subjects. The intrasulcal length, surface area, and local variability of the CS were measured. There were no significant differences in either the intrasulcal length or surface area of the anterior or posterior walls between the 2 groups. However, we observed that the controls had a pronounced left-larger-than-right asymmetry that was reduced in the musicians. Importantly, we found that the musicians showed greater local variability in the middle section (i.e., somatotopic hand area) of the right CS and the lower section of the left CS as compared with the controls. Further analysis revealed significantly negative correlations between the variability of the middle section of the right CS and the age of commencement of musical training. Our findings suggest that the musicians might be associated with plastic changes in the 3D morphology of the CS in response to long-term motor skill training.