Practical behavioral trials to advance evidence-based behavioral medicine
Practical behavioral trials to advance evidence-based behavioral medicine
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DOI：
10.1207/s15324796abm3101_3
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发表时间：
2006-01-01
影响因子：
3.8
通讯作者：
Spring, B
中科院分区：
文献类型：
--
作者：
Glasgow, RE;Davidson, KW;Spring, B
在行为医学的许多领域，研究与实践之间存在着明显的差距。这种差距部分是由于研究数据库解决临床医生、行政决策者和政策制定者最关心的问题的能力有限。因此，有人呼吁进行“实用临床试验”，比较临床上可行的替代干预措施，并评估对不同患者群体和环境中的临床和政策决策重要的多种结果。此类试验提供了巨大的潜力，并且在最佳研究设计和资金来源方面提出了有趣的挑战。我们讨论与行为医学实际临床试验相关的问题，提出实际行为试验（PBT）的需求，并描述将促进临床和政策决策的设计特征。这种类型的 PBT 有助于缩小研究与实践之间的差距，并推动循证行为医学领域的发展。我们讨论了 PBT 的潜在挑战和反对意见，最后为实际试验的设计、实施、报告和审查提供了建议。
There is a well-documented gap between research and practice in many areas of behavioral medicine. This gap is due in part to limitations in the capacity of the research database to address questions that are of central concern to clinicians, administrative decision makers, and policy makers. Thus, there has been a call for "practical clinical trials" that compare clinically viable alternative interventions and assess multiple outcomes important for clinical and policy decisions in diverse patient populations and settings. Such trials offer great potential, and they raise interesting challenges regarding optimal research design and source of funding. We discuss issues related to practical clinical trials in behavioral medicine, propose a need for practical behavioral trials (PBTs), and describe design features that will facilitate clinical and policy decision making. This type of PBT can help to close the gap between research and practice and advance the field of evidence-based behavioral medicine. We discuss potential challenges and objections to PBTs and conclude by providing recommendations for the design, conduct, reporting, and review of practical trials.